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Wilee is a bicycle messenger who rides a single-gear bike with no brakes. His routine delivery turns into a dangerous chase when his last package of the day is pursued by corrupt police officers.

The film follows a nonlinear narrative. It contains numerous flash-forward and flashback cuts, indicated with an overlaid digital clock showing the time advancing rapidly forward or backward to the next scene.

Wilee (Joseph Gordon-Levitt) is a disenchanted Columbia Law School graduate who has put off taking the bar exam because he could not bear to enter the humdrum life of the legal profession. He finds meaning and purpose in being employed as a thrill-seeking New York City bicycle messenger, despite arguments with his girlfriend and fellow bike messenger, Vanessa (Dania Ramirez), who insists that he should make something of himself.